| Long name: |
HRP Conjugated, Optineurin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Optineurin |
| Specificity: |
This is a highly specific antibody against Optineurin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
350-400/577 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human Optineurin |
| Gene ID number: |
10133 |
| Swiss Prot: |
Q96CV9 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family, Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation, May act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD), May constitute a cellular target for adenovirus E3 14, Mediates the interaction of Rab8 with the probable GTPase-activating protein TBC1D17 during Rab8-mediated endocytic trafficking, Negatively regulates the induction of IFNB in response to RNA virus infection, Plays a neuroprotective role in the eye and optic nerve, Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death, an inhibitor of TNF-alpha functions, and appears to function in the same pathway as SQSTM1 and CALCOCO2/NDP52, in exocytosis, in membrane trafficking, regulates Rab8 recruitnment to tubules emanating from the endocytic recycling compartment, such as cytoplasmic Salmonella enterica, such as of transferrin receptor (TFRC/TfR), targets ubiquitin-coated bacteria (xenophagy), thereby affecting cell death, through its interaction with myosin VI and Rab8, 7, Plays an important role in the maintenance of the Golgi complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ALS12, E3-14, FIP-2, FIP2, GLC1E, HIP-7, HIP7, HYPL, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, OPTN, Optic neuropathy-inducing protein, Optineurin, TFIIIA-INTP, Transcription factor IIIA-interacting protein, 7K-interacting protein, NRP |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
Optineurin Conjugated |
| Short name: |
Conjugated, Optineurin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, Optineurin (Antibody to) |
| Alternative technique: |
antibodies |