| Long name: |
ALEXA FLUOR 647 Conjugated, GRAP Polyclonal Antibody |
| Also known as: |
Anti-GRAP PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GRAP |
| Specificity: |
This is a highly specific antibody against GRAP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GRAP |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
For instance, GRB10 (also referred to as GRB-IR), GRB14 and Grap (for GRB2-related adapter protein), GRB7, Grap also associates with the Ras guanine nucleotide exchange factor Sos 1 via its amino terminal SH3 domain, Grap shares the highest degree of homology with GRB2 exhibiting 59% sequence identity with GRB2, Members include GRB2, Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific receptor sequences, The Grap SH2 domain is capable of binding to the activated stem cell factor receptor, While GRB10 and GRB14 are most closely related to GRB7, c-Kit and the erythropoietin receptor (EpoR), the GRB family of proteins lack a defined catalytic activity and are entirely composed of SH2 and SH3 domains, Many growth factors function by binding receptors with intrinsic tyrosine kinase activity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GRAP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GRAP |
| Short name: |
GRAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, GRAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4562 |
| Gene: |
GRAP |
More about : GRAP |
| Long gene name: |
GRB2-related adaptor protein |
| Locus: |
17p11, 2 |
| Discovery year: |
1998-09-29 |
| GenBank acession: |
U52518 |
| Entrez gene record: |
10750 |
| Pubmed identfication: |
8647802 8995379 |
| RefSeq identity: |
NM_006613 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000059436 |