| Long name: |
Biotin Conjugated, CLIC2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CLIC2 |
| Specificity: |
This is a highly specific antibody against CLIC2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CLIC2 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Because a direct association exists between a number of human chloride channel genes and a range of hereditary diseases, CLCs are involved in membrane potential stabilization, CLIC2 is a potential candidate for one of the many diseases linked to Xq28, The CLIC2 gene maps to chromosome Xq28 and contains 6 exons, The hereditary form of incontinentia pigmenti (IP2), The putative 247 amino acid protein chloride intracellular channel 2 (CLIC2), a critical component of all living cells, also designated XAP121, cell volume regulation and organic solute transport, for example, is a rare disorder characterized by abnormalities of the tissues and organs derived from the ectoderm and neuroectoderm that has been linked to Xq28, shares 60% identity with the CLIC1 protein and demonstrates expression in only fetal liver and adult skeletal muscle tissues, signal transduction, Chloride channels (CLCs) regulate cellular traffic of chloride ions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
XAP121 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CLIC2 Conjugated |
| Short name: |
Conjugated, CLIC2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CLIC2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2063 |
| Gene: |
CLIC2 |
More about : CLIC2 |
| Long gene name: |
chloride intracellular channel 2 |
| Locus: |
Xq28 |
| Discovery year: |
1997-10-17 |
| GenBank acession: |
AJ000217 |
| Entrez gene record: |
1193 |
| Pubmed identfication: |
9339381 |
| RefSeq identity: |
NM_001289 |
| Classification: |
Chloride intracellular channels |
| Havana BLAST/BLAT: |
OTTHUMG00000022660 |
| Locus Specific Databases: |
Mental Retardation database |