| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CLIC2 |
| Specificity: |
This antibody reacts specifically with CLIC2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CLIC2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Because a direct association exists between a number of human chloride channel genes and a range of hereditary diseases, CLCs are involved in membrane potential stabilization, CLIC2 is a potential candidate for one of the many diseases linked to Xq28, The CLIC2 gene maps to chromosome Xq28 and contains 6 exons, The hereditary form of incontinentia pigmenti (IP2), The putative 247 amino acid protein chloride intracellular channel 2 (CLIC2), a critical component of all living cells, also designated XAP121, cell volume regulation and organic solute transport, for example, is a rare disorder characterized by abnormalities of the tissues and organs derived from the ectoderm and neuroectoderm that has been linked to Xq28, shares 60% identity with the CLIC1 protein and demonstrates expression in only fetal liver and adult skeletal muscle tissues, signal transduction, Chloride channels (CLCs) regulate cellular traffic of chloride ions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
XAP121 |
| Also known as: |
CLIC2 Polyclonal Antibody |
| Other name: |
Anti-CLIC2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CLIC2 |
| Short name: |
Anti-CLIC2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CLIC2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2063 |
| Gene: |
CLIC2 |
More about : CLIC2 |
| Long gene name: |
chloride intracellular channel 2 |
| Locus: |
Xq28 |
| Discovery year: |
1997-10-17 |
| GenBank acession: |
AJ000217 |
| Entrez gene record: |
1193 |
| Pubmed identfication: |
9339381 |
| RefSeq identity: |
NM_001289 |
| Classification: |
Chloride intracellular channels |
| Havana BLAST/BLAT: |
OTTHUMG00000022660 |
| Locus Specific Databases: |
Mental Retardation database |