| Long name: |
ZAK/HCCS4 Primary Polyclonal Antibody |
| Also known as: |
ZAK/HCCS4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ZAK/HCCS4 |
| Specificity: |
This is a highly specific antibody against ZAK/HCCS4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZAK/HCCS4 |
| Gene ID number: |
51776 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Isoform 1, Isoform 1, Isoform 1 may have role in neoplastic cell transformation and cancer development, Pro-apoptotic, Regulates the JNK and p38 pathways, Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2, but not isoform 2, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers, phosphorylates histone H3 at 'Ser-28', Stress-activated component of a protein kinase signal transduction cascade |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cervical cancer suppressor gene 4 protein, HCCS 4, HCCS-4, HCCS4, Human cervical cancer suppressor gene 4 protein, Leucine zipper and sterile alpha mot containing kinase, Leucine zipper- and sterile alpha mot-containing kinase, MLK 7, MLK like mitogen activated protein triple kinase, MLK related kinase, MLK-like mitogen-activated protein triple kinase, MLK-related kinase, MLK7, MLT, MLTK, MLTK_HUMAN, MRK, Mitogen activated protein kinase kinase kinase MLT, Mitogen-activated protein kinase kinase kinase MLT, Mixed lineage kinase 7, Mixed lineage kinase related kinase, Mixed lineage kinase related kinase MRK beta, Mixed lineage kinase with a leucine zipper and a sterile alpha mot, Mixed lineage kinase-related kinase, Mlklak, Sterile alpha mot and leucine zipper containing kinase AZK, Sterile alpha mot- and leucine zipper-containing kinase AZK, ZAK, AZK |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ZAK/HCCS4 |
| Short name: |
ZAK/HCCS4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Mitogen-activated protein kinase kinase kinase MLT/HCCS4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
B230120H23Rik and IDBG-179557 and ENSMUSG00000004085 and 65964, BT, ZAK and IDBG-75233 and ENSG00000091436 and 51776, nuclei, this GO :0000075 and cell cycle checkpoint and biological process this GO :0000077 and DNA damage checkpoint and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004709 and MAP kinase kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008219 and cell death and biological process this GO :0008283 and cell proliferation and biological process this GO :0009314 and response to radiation and biological process this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004709 : MAP kinase kinase kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004709 : MAP kinase kinase kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0044822 : poly(A) RNA binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0044822 : poly(A) RNA binding, transferring phosphorus-containing groups and molecular function this GO :0030154 and cell differentiation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function, 55601 and IDBG-640550 and ENSBTAG00000001083 and 519251, Mitogen-activated protein kinase kinase kinase MLT |
| Identity: |
17797 |
| Gene: |
MAP3K20 |
More about : MAP3K20 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase 20 |
| Synonyms: |
MLTKalpha MLTKbeta ZAK MLTK MLK7 MRK |
| Synonyms name: |
ZAK1 homolog, leucine zipper and sterile-alpha motif kinase (Dictyostelium) mixed lineage kinase 7 |
| Locus: |
2q31, 1 |
| Discovery year: |
2016-10-19 |
| GenBank acession: |
AB049733 |
| Entrez gene record: |
51776 |
| Pubmed identfication: |
10924358 |
| RefSeq identity: |
NM_016653 |
| Classification: |
Mitogen-activated protein kinase kinase kinases |