| Long name: |
FITC Conjugated, GPR44 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR44 |
| Specificity: |
This is a highly specific antibody against GPR44 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
169-210/395 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GPR44/CD294 |
| Gene ID number: |
11251 |
| Swiss Prot: |
Q9Y5Y4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ADRBK1/GRK2, CRTH2 internalization can be regulated by diverse kinases such as, Coupled to the G(i)-protein, GPRK5/GRK5 and GRK6, PGD2 induced receptor internalization, PI3K signaling is also implicated in mediating PTGDR2 effects, PKA, PKC, Receptor activation is responsible, Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization, at least in part, in immune regulation and allergic/inflammation responses, Receptor for prostaglandin D2 (PGD2) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CRTH2 CD294 DP2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPR44 Conjugated |
| Short name: |
FITC Conjugated, GPR44 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GPR44 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4502 |
| Gene: |
PTGDR2 |
More about : PTGDR2 |
| Long gene name: |
prostaglandin D2 receptor 2 |
| Synonyms gene: |
GPR44 |
| Synonyms gene name: |
G protein-coupled receptor 44 |
| Synonyms name: |
chemoattractant receptor homologous molecule expressed on T helper type 2 cells |
| Locus: |
11q12, 2 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
AF118265 |
| Entrez gene record: |
11251 |
| Pubmed identfication: |
10036181 |
| RefSeq identity: |
NM_004778 |
| Classification: |
Prostaglandin (prostanoid) receptors CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000167796 |