| Long name: |
GPR44 Primary Polyclonal Antibody |
| Also known as: |
GPR44 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GPR44 |
| Specificity: |
This is a highly specific antibody against GPR44 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
169-210/395 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR44/CD294 |
| Gene ID number: |
11251 |
| Swiss Prot: |
Q9Y5Y4 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ADRBK1/GRK2, CRTH2 internalization can be regulated by diverse kinases such as, Coupled to the G(i)-protein, GPRK5/GRK5 and GRK6, PGD2 induced receptor internalization, PI3K signaling is also implicated in mediating PTGDR2 effects, PKA, PKC, Receptor activation is responsible, Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization, at least in part, in immune regulation and allergic/inflammation responses, Receptor for prostaglandin D2 (PGD2) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD294, CRTH2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, DL1R, G-protein coupled receptor 44, GPR44, PTGDR2, Prostaglandin D2 receptor 2, DP2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPR44 |
| Short name: |
GPR44 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GPR44 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4502 |
| Gene: |
PTGDR2 |
More about : PTGDR2 |
| Long gene name: |
prostaglandin D2 receptor 2 |
| Synonyms gene: |
GPR44 |
| Synonyms gene name: |
G protein-coupled receptor 44 |
| Synonyms: |
CRTH2 CD294 DP2 |
| Synonyms name: |
chemoattractant receptor homologous molecule expressed on T helper type 2 cells |
| Locus: |
11q12, 2 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
AF118265 |
| Entrez gene record: |
11251 |
| Pubmed identfication: |
10036181 |
| RefSeq identity: |
NM_004778 |
| Classification: |
Prostaglandin (prostanoid) receptors CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000167796 |