| Long name: |
FITC Conjugated, GPR124/TEM5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR124 |
| Specificity: |
This is a highly specific antibody against GPR124 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human G protein coupled receptor 124 |
| Gene ID number: |
25960 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1), TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies, TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis, TEM5 is a seven-pass transmembrane receptor, TEM7 and TEM8 span the membrane once, TEM7 is highly expressed in tumor endothelium and neurons, TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues, Therefore, These include TEM1 (endosialin), whereas TEM1, Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
TEM5 DKFZp434C211 DKFZp434J0911 KIAA1531 FLJ14390 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPR124/TEM5 Conjugated |
| Short name: |
FITC Conjugated, GPR124/TEM5 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GPR124/TEM5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17849 |
| Gene: |
ADGRA2 |
More about : ADGRA2 |
| Long gene name: |
adhesion G protein-coupled receptor A2 |
| Synonyms gene: |
GPR124 |
| Synonyms gene name: |
G protein-coupled receptor 124 |
| Synonyms name: |
tumor endothelial marker 5 |
| Locus: |
8p11, 23 |
| Discovery year: |
2003-02-25 |
| GenBank acession: |
AB040964 |
| Entrez gene record: |
25960 |
| Pubmed identfication: |
11559528 12565841 25713288 |
| Classification: |
Immunoglobulin like domain containing Adhesion G protein-coupled receptors, subfamily A |
| Havana BLAST/BLAT: |
OTTHUMG00000156182 |