| known also as: |
Anti-GOAT ANTI HUMAN CD154:Biotin |
| known also as: |
Caprine ANTI HUMAN CD154:Biotin |
| known also as: |
Caprinae ANTI Homo sapiens CD154:Biotin |
| known also as: |
CD154 |
| Other names: |
CD40 antigen ligand, CD40 ligand, CD40 ligand, CD40 ligand, CD40-L, T-B cell-activating molecule, T-cell antigen Gp39, T-cell antigen Gp39, TNF-related activation protein, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, tumor necrosis factor (ligand) superfamily member 5, CD40 ligand |
| Gene name: |
CD154 |
| Other gene names: |
CD154, CD40-L, CD40L, CD40L, CD40LG, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TNFSF5, TRAP, TRAP, TRAP, gp39, hCD40L, CD40LG |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
_x000D__x000D_CD154 is expressed predominantly on activated CD4+ T lymphocytes, a member of the TNF receptor superfamily, also designated CD40L (sCD40 Ligand), and acts as a costimulatory molecule in B cell differentiation/proliferation, and cytokines secreted by activated T cells, comprising the full-length of the TNF homologous region of CD154, immunoglobulin switching and germinal centre formation, through interaction with the CD40 receptor on B cells, CD154 This item is specific for the soluble form of human CD154, _x000D_ |
| Form/Appearance: |
Biotin (Purified IgG conjugated to Biotin - lyophilised) |
| Concentration: |
IgG concentration 50ug/ml |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Conjugation: |
Biotinylated |
| Gene target: |
CD154: |
| Short name: |
GOAT ANTI HUMAN CD154: Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
sapiens CD154:biotinilated (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
11935 |
| Gene: |
CD40LG |
More about : CD40LG |
| Long gene name: |
CD40 ligand |
| Synonyms gene: |
HIGM1 IMD3 TNFSF5 |
| Synonyms gene name: |
member 5 (hyper-IgM syndrome) , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
CD40L TRAP gp39 hCD40L CD154 |
| Synonyms name: |
CD40 antigen ligand tumor necrosis factor (ligand) superfamily member 5 T-B cell-activating molecule TNF-related activation protein hyper-IgM syndrome |
| Locus: |
Xq26, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
X67878 |
| Entrez gene record: |
959 |
| Pubmed identfication: |
1427881 7678782 |
| RefSeq identity: |
NM_000074 |
| Classification: |
Endogenous ligands Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000022512 |
| Locus Specific Databases: |
CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome Mental Retardation database LRG_141 |