| Also known as: |
CD154 |
| Other names: |
CD40 antigen ligand, CD40 ligand, CD40 ligand, CD40 ligand, CD40-L, T-B cell-activating molecule, T-cell antigen Gp39, T-cell antigen Gp39, TNF-related activation protein, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, tumor necrosis factor (ligand) superfamily member 5, CD40 ligand |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD154 |
| Other gene names: |
CD154, CD40-L, CD40L, CD40L, CD40LG, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TNFSF5, TRAP, TRAP, TRAP, gp39, hCD40L, CD40LG |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
MK13A4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD154 is expressed on activated T lymphocytes, Clone MK13A4 has been reported to block binding of CD40 ligand to its receptor CD40, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 32kD glycoprotein also known as CD40 ligand, predominantly CD4+ve cells and also on some basophils and mast cells, CD154 This item recognises the human CD154 cell surface antigen |
| Form/Appearance: |
Biotin (Purified IgG conjugated to Biotin - liquid) |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Biotinylated |
| Gene target: |
CD154: |
| Short name: |
MOUSE Anti-HUMAN CD154: Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
sapiens CD154:biotinilated (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11935 |
| Gene: |
CD40LG |
More about : CD40LG |
| Long gene name: |
CD40 ligand |
| Synonyms gene: |
HIGM1 IMD3 TNFSF5 |
| Synonyms gene name: |
member 5 (hyper-IgM syndrome) , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
CD40L TRAP gp39 hCD40L CD154 |
| Synonyms name: |
CD40 antigen ligand tumor necrosis factor (ligand) superfamily member 5 T-B cell-activating molecule TNF-related activation protein hyper-IgM syndrome |
| Locus: |
Xq26, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
X67878 |
| Entrez gene record: |
959 |
| Pubmed identfication: |
1427881 7678782 |
| RefSeq identity: |
NM_000074 |
| Classification: |
Endogenous ligands Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000022512 |
| Locus Specific Databases: |
CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome Mental Retardation database LRG_141 |