| Long name: |
Biotin Conjugated, GNRH2/GnRH II Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GNRH2/GnRH II |
| Specificity: |
This is a highly specific antibody against GNRH2/GnRH II |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GNRH2/GnRH II |
| Gene ID number: |
2797 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
GnRH II is highly expressed outside the brain, GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary, GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins, GnRH is expressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells, GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the medianeminence, Gonadotropin releasing hormone (GnRH), In addition to hypothalamic GnRH (GnRH I), Unlike GnRH I, a second GnRH form (GnRH II) functions primarily in the midbrain, also known as GnRH-associated peptide, bone marrow and prostate, is a decapeptide that is an important molecule in the hypothalamic-pituitary-gonadal axis control circuit, luliberin or gonadorelin, luteinizing hormone releasing hormone (LHRH), particularly in the kidney, suggesting that it may have multiple functions, Human reproduction is controlled by the hypothalaic-pituitary gonadal axis laid down early in fetal development |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GNRH2/GnRH II Conjugated |
| Short name: |
Conjugated, GNRH2/GnRH II Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GNRH2/GnRH II (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4420 |
| Gene: |
GNRH2 |
More about : GNRH2 |
| Long gene name: |
gonadotropin releasing hormone 2 |
| Synonyms gene name: |
gonadotropin-releasing hormone 2 |
| Synonyms name: |
progonadoliberin-2 |
| Locus: |
20p13 |
| Discovery year: |
1998-01-20 |
| GenBank acession: |
AF036329 |
| Entrez gene record: |
2797 |
| Pubmed identfication: |
9419371 12447356 |
| RefSeq identity: |
NM_001501 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000031723 |