| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GNRH2/GnRH II |
| Specificity: |
This antibody reacts specifically with GNRH2/GnRH II |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GNRH2/GnRH II |
| Gene ID: |
2797 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GnRH II is highly expressed outside the brain, GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary, GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins, GnRH is expressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells, GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the medianeminence, Gonadotropin releasing hormone (GnRH), In addition to hypothalamic GnRH (GnRH I), Unlike GnRH I, a second GnRH form (GnRH II) functions primarily in the midbrain, also known as GnRH-associated peptide, bone marrow and prostate, is a decapeptide that is an important molecule in the hypothalamic-pituitary-gonadal axis control circuit, luliberin or gonadorelin, luteinizing hormone releasing hormone (LHRH), particularly in the kidney, suggesting that it may have multiple functions, Human reproduction is controlled by the hypothalaic-pituitary gonadal axis laid down early in fetal development |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GNRH2/GnRH II Polyclonal Antibody |
| Other name: |
Anti-GNRH2/GnRH II Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GNRH2/GnRH II |
| Short name: |
Anti-GNRH2/GnRH II (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GNRH2/GnRH II (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4420 |
| Gene: |
GNRH2 |
More about : GNRH2 |
| Long gene name: |
gonadotropin releasing hormone 2 |
| Synonyms gene name: |
gonadotropin-releasing hormone 2 |
| Synonyms name: |
progonadoliberin-2 |
| Locus: |
20p13 |
| Discovery year: |
1998-01-20 |
| GenBank acession: |
AF036329 |
| Entrez gene record: |
2797 |
| Pubmed identfication: |
9419371 12447356 |
| RefSeq identity: |
NM_001501 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000031723 |