| Catalog number: | bs-13360R-Cy7 |
|---|---|
| Price: | 489 € |
| Supplier: | Bioss Polyclonal Antibodies |
| Product name: | GIT2 Antibody, Cy7 Conjugated |
| Quantity: | 100 microliters |
| Related search: |
| Long name: | Cy7 Conjugated, GIT2 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy7 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | GIT2 |
| Specificity: | This is a highly specific antibody against GIT2 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human GIT2 |
| Gene ID number: | 9815 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3, thus reducing b2-adrenergic receptor signaling (5), which are involved in vesicular trafficking (5, 2), 4), 6), Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1 |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 743nm/767nm |
| Synonyms: | KIAA0148 PKL |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: | GIT2 Conjugated |
| Short name: | Conjugated, GIT2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy7 |
| Alternative name: | cyanine 7 coupled, GIT2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4273 |
| Gene: | GIT2 | More about : GIT2 |
| Long gene name: | GIT ArfGAP 2 |
| Synonyms gene name: | G protein-coupled receptor kinase interactor 2 G protein-coupled receptor kinase interacting ArfGAP 2 |
| Synonyms name: | Paxillin kinase linker |
| Locus: | 12q24, 11 |
| Discovery year: | 2000-07-31 |
| GenBank acession: | AF124491 |
| Entrez gene record: | 9815 |
| Pubmed identfication: | 9826657 10896954 |
| RefSeq identity: | NM_057169 |
| Classification: | Ankyrin repeat domain containing ArfGAPs |
| Havana BLAST/BLAT: | OTTHUMG00000169313 |
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