| Long name: |
FITC Conjugated, GFPT2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GFPT2 |
| Specificity: |
This is a highly specific antibody against GFPT2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GFPT2 |
| Gene ID number: |
9945 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Containing one glutamine amidotransferase type-2 domain and two SIS domains, Expressed in spinal cord, GFAT2 gene variants have been linked to type 2 diabetes, GFAT2 is encoded by a gene that maps to human chromosome 5q35, GFAT2 regulates glucose entry into the HBP and likely controls the availability of precursors for N- and O-linked protein glycosylation, also known as D-fructose-6-phosphate amidotransferase 2 or hexosephosphate aminotransferase 2, and increased GFPT2 mRNA levels, diabetic nephropathy, heart and placenta, is a 682 amino acid protein and isoenzyme of GFAT1, the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthetic pathway (HBP), which is a relatively minor branch of glycolysis, 3, GFPT2 (glutamine-fructose-6-phosphate transaminase 2) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GFAT2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GFPT2 Conjugated |
| Short name: |
FITC Conjugated, GFPT2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GFPT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4242 |
| Gene: |
GFPT2 |
More about : GFPT2 |
| Long gene name: |
glutamine-fructose-6-phosphate transaminase 2 |
| Synonyms name: |
glutamine: fructose-6-phosphate aminotransferase 2 |
| Locus: |
5q35, 3 |
| Discovery year: |
1999-05-06 |
| GenBank acession: |
AB016789 |
| Entrez gene record: |
9945 |
| Pubmed identfication: |
10198162 |
| RefSeq identity: |
NM_005110 |
| Havana BLAST/BLAT: |
OTTHUMG00000163442 |