| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GFPT2 |
| Specificity: |
This antibody reacts specifically with GFPT2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GFPT2 |
| Gene ID: |
9945 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Containing one glutamine amidotransferase type-2 domain and two SIS domains, Expressed in spinal cord, GFAT2 gene variants have been linked to type 2 diabetes, GFAT2 is encoded by a gene that maps to human chromosome 5q35, GFAT2 regulates glucose entry into the HBP and likely controls the availability of precursors for N- and O-linked protein glycosylation, also known as D-fructose-6-phosphate amidotransferase 2 or hexosephosphate aminotransferase 2, and increased GFPT2 mRNA levels, diabetic nephropathy, heart and placenta, is a 682 amino acid protein and isoenzyme of GFAT1, the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthetic pathway (HBP), which is a relatively minor branch of glycolysis, 3, GFPT2 (glutamine-fructose-6-phosphate transaminase 2) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GFAT2 |
| Also known as: |
GFPT2 Polyclonal Antibody |
| Other name: |
Anti-GFPT2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GFPT2 |
| Short name: |
Anti-GFPT2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GFPT2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4242 |
| Gene: |
GFPT2 |
More about : GFPT2 |
| Long gene name: |
glutamine-fructose-6-phosphate transaminase 2 |
| Synonyms name: |
glutamine: fructose-6-phosphate aminotransferase 2 |
| Locus: |
5q35, 3 |
| Discovery year: |
1999-05-06 |
| GenBank acession: |
AB016789 |
| Entrez gene record: |
9945 |
| Pubmed identfication: |
10198162 |
| RefSeq identity: |
NM_005110 |
| Havana BLAST/BLAT: |
OTTHUMG00000163442 |