| Long name: |
FITC Conjugated, GCM2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GCM2 |
| Specificity: |
This is a highly specific antibody against GCM2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GCM2 |
| Gene ID number: |
9247 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
GCM2 contains one N-terminal GCM domain, GCM2 is a transcription factor that acts as an essential regulator of parathyroid development, GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells, Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, also known as Chorion-specific transcription factor GCMb, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia, is a 506 amino acid nuclear protein, which has DNA binding activity, Glial cells missing homolog 2 (GCM2) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
hGCMb |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GCM2 Conjugated |
| Short name: |
FITC Conjugated, GCM2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, glial cells missing homolog 2 (Drosophila) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0030154 and cell differentiation and biological process this GO :0030643 and cellular phosphate ion homeostasis and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0060017 and parathyroid gland development and biological process this GO :0071310 and cellular response to organic substance and biological process, GCM2 and IDBG-61420 and ENSG00000124827 and 9247, GCM2 and IDBG-636225 and ENSBTAG00000018787 and 539454, GCMB and hGCMb, Gcm2 and IDBG-146771 and ENSMUSG00000021362 and 107889, metal ion binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, glial cells missing homolog 2 (Drosophila) |
| Identity: |
4198 |
| Gene: |
GCM2 |
More about : GCM2 |
| Long gene name: |
glial cells missing homolog 2 |
| Synonyms gene: |
GCMB |
| Synonyms gene name: |
glial cells missing (Drosophila) homolog b glial cells missing homolog 2 (Drosophila) |
| Locus: |
6p24, 2 |
| Discovery year: |
1998-10-02 |
| GenBank acession: |
AF079550 |
| Entrez gene record: |
9247 |
| Pubmed identfication: |
9928992 |
| Havana BLAST/BLAT: |
OTTHUMG00000014249 |