| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GCM2 |
| Specificity: |
This antibody reacts specifically with GCM2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GCM2 |
| Gene ID: |
9247 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GCM2 contains one N-terminal GCM domain, GCM2 is a transcription factor that acts as an essential regulator of parathyroid development, GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells, Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, also known as Chorion-specific transcription factor GCMb, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia, is a 506 amino acid nuclear protein, which has DNA binding activity, Glial cells missing homolog 2 (GCM2) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
hGCMb |
| Also known as: |
GCM2 Polyclonal Antibody |
| Other name: |
Anti-GCM2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GCM2 |
| Short name: |
Anti-GCM2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-glial cells missing homolog 2 (Drosophila) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0030154 and cell differentiation and biological process this GO :0030643 and cellular phosphate ion homeostasis and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0060017 and parathyroid gland development and biological process this GO :0071310 and cellular response to organic substance and biological process, GCM2 and IDBG-61420 and ENSG00000124827 and 9247, GCM2 and IDBG-636225 and ENSBTAG00000018787 and 539454, GCMB and hGCMb, Gcm2 and IDBG-146771 and ENSMUSG00000021362 and 107889, metal ion binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, glial cells missing homolog 2 (Drosophila) |
| Identity: |
4198 |
| Gene: |
GCM2 |
More about : GCM2 |
| Long gene name: |
glial cells missing homolog 2 |
| Synonyms gene: |
GCMB |
| Synonyms gene name: |
glial cells missing (Drosophila) homolog b glial cells missing homolog 2 (Drosophila) |
| Locus: |
6p24, 2 |
| Discovery year: |
1998-10-02 |
| GenBank acession: |
AF079550 |
| Entrez gene record: |
9247 |
| Pubmed identfication: |
9928992 |
| Havana BLAST/BLAT: |
OTTHUMG00000014249 |