| Long name: |
Cy3 Conjugated, GCDH Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GCDH |
| Specificity: |
This is a highly specific antibody against GCDH |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GCDH |
| Gene ID number: |
2639 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the gene encoding GCDH are the cause of glutaric acidemia type I (GA-I), Existing as a homotetramer, GCDH uses FAD as a cofactor to catalyze the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine and L-tryptophan metabolism, While GCDH exists as both a long and short isoform, an autosomal recessive disorder that is characterized by the accumulation of glutaconic acid and is associated with such symptoms as progressive dystonia and athetosis due to gliosis and neuronal loss in the basal ganglia, only the long isoform is a functionally active protein, GCDH is a 438 amino acid protein that localizes to the mitochondrial matrix and belongs to the acyl-CoA dehydrogenase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
ACAD5 |
| Properties: |
1 of the GCDH Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GCDH Conjugated |
| Short name: |
Conjugated, GCDH Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, GCDH (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4189 |
| Gene: |
GCDH |
More about : GCDH |
| Long gene name: |
glutaryl-CoA dehydrogenase |
| Synonyms gene name: |
glutaryl-Coenzyme A dehydrogenase |
| Locus: |
19p13, 13 |
| Discovery year: |
1992-12-17 |
| GenBank acession: |
AF012342 |
| Entrez gene record: |
2639 |
| Pubmed identfication: |
1438360 8088809 |
| Classification: |
Acyl-CoA dehydrogenase family |
| Havana BLAST/BLAT: |
OTTHUMG00000180561 |