| Catalog number: | bs-13295R-FITC |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | GATA4 (Ser105) Antibody, FITC Conjugated |
| Quantity: | 100ul |
| Related search: |
| Long name: | FITC Conjugated, GATA4 (Ser105) Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Anti-FITC Antibody |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | GATA4 Ser105 |
| Specificity: | This is a highly specific antibody against GATA4 Ser105 |
| Modification: | Phosphorylation |
| Modification site: | Ser105 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human GATA4 around the phosphorylation site of Ser105 |
| Gene ID number: | 2626 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | AGATCTTA, Although expression patterns of the various GATA transcription factors may overlap, Both GATA-4 and GATA-6 are found in heart, GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes, GATA-2 is expressed in embryonic brain and liver, GATA-3 is highly expressed in T lymphocytes, GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors, GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart, HeLa and endothelial cells, It is an essential component in the generation of the erythroid lineage, Studies with a modified GATA consensus sequence, This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1, as well as in erythroid cells, but not GATA-4 expression, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites, lung and liver tissues exhibit GATA-6, pancreas and ovary, Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 494nm/518nm |
| Properties: | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | GATA4 (Ser105) Conjugated |
| Short name: | FITC Conjugated, GATA4 (Ser105) Antibody |
| Technique: | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | FITC |
| Alternative name: | fluorecein coupled, GATA4 (Ser105) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4173 |
| Gene: | GATA4 | More about : GATA4 |
| Long gene name: | GATA binding protein 4 |
| Synonyms gene name: | GATA-binding protein 4 |
| Locus: | 8p23, 1 |
| Discovery year: | 1994-11-30 |
| GenBank acession: | AK097060 |
| Entrez gene record: | 2626 |
| Pubmed identfication: | 7665171 |
| RefSeq identity: | NM_002052 |
| Classification: | GATA zinc finger domain containing |
| Havana BLAST/BLAT: | OTTHUMG00000090800 |
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