| Long name: |
Cy3 Conjugated, GATA3 (Ser308) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GATA3 Ser308 |
| Specificity: |
This is a highly specific antibody against GATA3 Ser308 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser308 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser308 |
| Gene ID number: |
2625 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AGATCTTA, Although expression patterns of the various GATA transcription factors may overlap, Both GATA-4 and GATA-6 are found in heart, GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes, GATA-2 is expressed in embryonic brain and liver, GATA-3 is highly expressed in T lymphocytes, GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors, GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart, HeLa and endothelial cells, It is an essential component in the generation of the erythroid lineage, Studies with a modified GATA consensus sequence, This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1, as well as in erythroid cells, but not GATA-4 expression, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites, lung and liver tissues exhibit GATA-6, pancreas and ovary, Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
HDR |
| Properties: |
1 of the GATA3 (Ser308) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GATA3 (Ser308) Conjugated |
| Short name: |
Conjugated, GATA3 (Ser308) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, GATA3 (Ser308) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4172 |
| Gene: |
GATA3 |
More about : GATA3 |
| Long gene name: |
GATA binding protein 3 |
| Synonyms gene name: |
GATA-binding protein 3 |
| Locus: |
10p14 |
| Discovery year: |
1992-11-03 |
| GenBank acession: |
X55122 |
| Entrez gene record: |
2625 |
| Pubmed identfication: |
2050118 15087456 |
| RefSeq identity: |
NM_001002295 |
| Classification: |
GATA zinc finger domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017640 |