| Long name: |
GATA3 (Ser308) Primary Polyclonal Antibody |
| Also known as: |
GATA3 (Ser308) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GATA3 Ser308 |
| Specificity: |
This is a highly specific antibody against GATA3 Ser308 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser308 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser308 |
| Gene ID number: |
2625 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AGATCTTA, Although expression patterns of the various GATA transcription factors may overlap, Both GATA-4 and GATA-6 are found in heart, GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes, GATA-2 is expressed in embryonic brain and liver, GATA-3 is highly expressed in T lymphocytes, GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors, GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart, HeLa and endothelial cells, It is an essential component in the generation of the erythroid lineage, Studies with a modified GATA consensus sequence, This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1, as well as in erythroid cells, but not GATA-4 expression, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites, lung and liver tissues exhibit GATA-6, pancreas and ovary, Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GATA 3, GATA binding factor 3, GATA binding protein 3, GATA-3, GATA-binding factor 3, GATA3, GATA3 phospho Ser308, GATA3_HUMAN, HDR, MGC2346, MGC5199, MGC5445, Trans acting T cell specic transcription factor GATA 3, Trans-acting T-cell-specic transcription factor GATA-3, p-GATA3 Ser308, p-GATA3 phospho S308, GATA3 phospho S308 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GATA3 (Ser308) |
| Short name: |
GATA3 (Ser308) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GATA3 (Ser308) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4172 |
| Gene: |
GATA3 |
More about : GATA3 |
| Long gene name: |
GATA binding protein 3 |
| Synonyms gene name: |
GATA-binding protein 3 |
| Synonyms: |
HDR |
| Locus: |
10p14 |
| Discovery year: |
1992-11-03 |
| GenBank acession: |
X55122 |
| Entrez gene record: |
2625 |
| Pubmed identfication: |
2050118 15087456 |
| RefSeq identity: |
NM_001002295 |
| Classification: |
GATA zinc finger domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017640 |