| Long name: |
ALEXA FLUOR 647 Conjugated, RASA1 Polyclonal Antibody |
| Also known as: |
Anti-RASA1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RASA1 |
| Specificity: |
This is a highly specific antibody against RASA1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ras GTPase-activating protein 1 |
| Gene ID Number: |
5921 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4, Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, Rab 3A and Rap 1, The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6, and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1, have also been described (8, hydrolysis of their bound GTP to GDP, including Rho, is impaired as a result of specific mutations (3), p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3), 2), 5), 7), 9), The mammalian c-H- |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
GAP CM-AVM p120GAP p120RASGAP p120 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the RASA1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
RASA1 |
| Short name: |
RASA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, RAS p21 protein activator (GTPase activating protein) 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CM-AVM and CMAVM and GAP and p120GAP and p120RASGAP and PKWS and RASA and RASGAP, GTPase binding, Plasma membranes, RASA1 and IDBG-32785 and ENSG00000145715 and 5921, Rasa1 and IDBG-170464 and ENSMUSG00000021549 and 218397, this GO :0000281 and mitotic cytokinesis and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001726 and ruffle and cellular component this GO :0001948 and glycoprotein binding and molecular function this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0005096 and GTPase activator activity and molecular function this GO :0005099 and Ras GTPase activator activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009790 and embryo development and biological process this GO :0019870 and potassium channel inhibitor activity and molecular function this GO :0030833 and regulation of actin filament polymerization and biological process this GO :0031235 and intrinsic component of the cytoplasmic side of the plasma membrane and cellular component this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0046580 and negative regulation of Ras protein signal transduction and biological process this GO :0051020 and GTPase binding and molecular function this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051252 and regulation of RNA metabolic process and biological process, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0005096 : GTPase activator activity and also this GO :0005099 : Ras GTPase activator activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0019870 : potassium channel inhibitor activity and also this GO :0051020 : GTPase binding, this GO :0005096 : GTPase activator activity, this GO :0005099 : Ras GTPase activator activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0019870 : potassium channel inhibitor activity, this GO :0051020 : GTPase binding, 102247 and IDBG-646529 and ENSBTAG00000009565 and 282032, RAS p21 protein activator (GTPase activating protein) 1 |
| Identity: |
9871 |
| Gene: |
RASA1 |
More about : RASA1 |
| Long gene name: |
RAS p21 protein activator 1 |
| Synonyms gene: |
RASA |
| Synonyms gene name: |
RAS p21 protein activator (GTPase activating protein) 1 |
| Synonyms name: |
capillary malformation-arteriovenous malformation p120 RAS GTPase activating protein |
| Locus: |
5q14, 3 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
5921 |
| Pubmed identfication: |
15917201 |
| RefSeq identity: |
NM_002890 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing C2 and RasGAP domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000162605 |
| Locus Specific Databases: |
SH2base: Database for pathogenic SH2 domain mutations |