| Long name: |
Cy5 Conjugated, GABPA/NRF2A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABPA/NRF2A |
| Specificity: |
This is a highly specific antibody against GABPA/NRF2A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GABPA/NRF2A |
| Gene ID number: |
2551 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini, GABP beta, GABP beta is expressed in both the cytoplasm and the nucleus, GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, In primary neuronal cultures, The GABP alpha beta tetrameric complex performs many different functions, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription, both of which can modify GABP-dependent transcription in vitro and in vivo, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, such as stimulating transcription of the adenovirus E4 gene, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, whereas GABP alpha is expressed mainly in the nucleus, The transcription factor GA-binding protein (GABP) is composed of two subunits |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
E4TF1A NFT2 NRF2 E4TF1-60 NRF2A |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GABPA/NRF2A Conjugated |
| Short name: |
Conjugated, GABPA/NRF2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, GABPA/NRF2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4071 |
| Gene: |
GABPA |
More about : GABPA |
| Long gene name: |
GA binding protein transcription factor alpha subunit |
| Synonyms gene name: |
GA-binding protein transcription factor, alpha subunit (60kD) GA binding protein transcription factor, alpha subunit 60kDa |
| Synonyms name: |
human nuclear respiratory factor-2 subunit alpha nuclear respiratory factor 2 alpha subunit |
| Locus: |
21q21, 3 |
| Discovery year: |
1994-01-18 |
| Entrez gene record: |
2551 |
| Pubmed identfication: |
8441384 |
| RefSeq identity: |
NM_002040 |
| Classification: |
ETS transcription factor family |
| Havana BLAST/BLAT: |
OTTHUMG00000078443 |