| Long name: |
GABPA/NRF2A Primary Polyclonal Antibody |
| Also known as: |
GABPA/NRF2A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GABPA/NRF2A |
| Specificity: |
This is a highly specific antibody against GABPA/NRF2A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GABPA/NRF2A |
| Gene ID number: |
2551 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini, GABP beta, GABP beta is expressed in both the cytoplasm and the nucleus, GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, In primary neuronal cultures, The GABP alpha beta tetrameric complex performs many different functions, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription, both of which can modify GABP-dependent transcription in vitro and in vivo, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, such as stimulating transcription of the adenovirus E4 gene, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, whereas GABP alpha is expressed mainly in the nucleus, The transcription factor GA-binding protein (GABP) is composed of two subunits |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E4TF1 60, E4TF1A, GA binding protein alpha chain, GA binding protein transcription factor alpha subunit, GA binding protein transcription factor alpha subunit 60kDa, GA-binding protein alpha chain, GABP A, GABP alpha subunit, GABP alpha subunit, GABP subunit alpha, GABPA_HUMAN, Gabpa, Human nuclear respiratory factor 2 subunit alpha, NFT 2, NFT2, NRF 2, NRF 2A, NRF2, NRF2A, Nuclear respiratory factor 2 alpha subunit, Nuclear respiratory factor 2 subunit alpha, Nuclear respiratory factor 2 subunit alpha, RCH04A07, Transcription factor E4TF1 60, Transcription factor E4TF1 60, Transcription factor E4TF1-60, E4TF 1A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GABPA/NRF2A |
| Short name: |
GABPA/NRF2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GABPA/NRF2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4071 |
| Gene: |
GABPA |
More about : GABPA |
| Long gene name: |
GA binding protein transcription factor alpha subunit |
| Synonyms gene name: |
GA-binding protein transcription factor, alpha subunit (60kD) GA binding protein transcription factor, alpha subunit 60kDa |
| Synonyms: |
E4TF1A NFT2 NRF2 E4TF1-60 NRF2A |
| Synonyms name: |
human nuclear respiratory factor-2 subunit alpha nuclear respiratory factor 2 alpha subunit |
| Locus: |
21q21, 3 |
| Discovery year: |
1994-01-18 |
| Entrez gene record: |
2551 |
| Pubmed identfication: |
8441384 |
| RefSeq identity: |
NM_002040 |
| Classification: |
ETS transcription factor family |
| Havana BLAST/BLAT: |
OTTHUMG00000078443 |