| Long name: |
ALEXA FLUOR 647 Conjugated, GABPA/NRF2A Polyclonal Antibody |
| Also known as: |
Anti-GABPA/NRF2A PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABPA/NRF2A |
| Specificity: |
This is a highly specific antibody against GABPA/NRF2A |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GABPA/NRF2A |
| Gene ID Number: |
2551 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini, GABP beta, GABP beta is expressed in both the cytoplasm and the nucleus, GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, In primary neuronal cultures, The GABP alpha beta tetrameric complex performs many different functions, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription, both of which can modify GABP-dependent transcription in vitro and in vivo, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, such as stimulating transcription of the adenovirus E4 gene, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, whereas GABP alpha is expressed mainly in the nucleus, The transcription factor GA-binding protein (GABP) is composed of two subunits |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
E4TF1A NFT2 NRF2 E4TF1-60 NRF2A |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GABPA/NRF2A Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GABPA/NRF2A |
| Short name: |
GABPA/NRF2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, GABPA/NRF2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4071 |
| Gene: |
GABPA |
More about : GABPA |
| Long gene name: |
GA binding protein transcription factor alpha subunit |
| Synonyms gene name: |
GA-binding protein transcription factor, alpha subunit (60kD) GA binding protein transcription factor, alpha subunit 60kDa |
| Synonyms name: |
human nuclear respiratory factor-2 subunit alpha nuclear respiratory factor 2 alpha subunit |
| Locus: |
21q21, 3 |
| Discovery year: |
1994-01-18 |
| Entrez gene record: |
2551 |
| Pubmed identfication: |
8441384 |
| RefSeq identity: |
NM_002040 |
| Classification: |
ETS transcription factor family |
| Havana BLAST/BLAT: |
OTTHUMG00000078443 |