| Long name: |
FITC Conjugated, GABRP/GABA A receptor pi Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABRP/GABA A receptor pi |
| Specificity: |
This is a highly specific antibody against GABRP/GABA A receptor pi |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GABRP/GABA A receptor pi |
| Gene ID number: |
2568 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both GABAA and GABAC are ligand-gated ion channels, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC, In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid), however, they are structurally and functionally distinct, GAD-65 and GAD-67 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
GABRP/GABA A receptor pi Conjugated |
| Short name: |
FITC Conjugated, GABRP/GABA A receptor pi Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GABRP/GABA A receptor pi (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4089 |
| Gene: |
GABRP |
More about : GABRP |
| Long gene name: |
gamma-aminobutyric acid type A receptor pi subunit |
| Synonyms gene name: |
gamma-aminobutyric acid (GABA) A receptor, pi |
| Synonyms name: |
GABA(A) receptor, pi |
| Locus: |
5q35, 1 |
| Discovery year: |
1997-06-18 |
| GenBank acession: |
U95367 |
| Entrez gene record: |
2568 |
| Pubmed identfication: |
9182563 |
| RefSeq identity: |
NM_014211 |
| Classification: |
Gamma-aminobutyric acid type A receptor subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000130443 |