| Long name: |
PE Conjugated, CCL5/RANTES Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
PE |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCL5/RANTES |
| Specificity: |
This is a highly specific antibody against CCL5/RANTES |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
71-89/91 |
| Subcellular location: |
Helical, Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human CCL5 |
| Gene ID number: |
6352 |
| Swiss Prot: |
P13501 |
| Tested applications: |
FCM |
| Recommended dilutions: |
FCM(1:20-100) |
| Crossreactivity: |
Bovine, Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Akt and MAP kinases, By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485), CCR3, CCR4 and CCR5, Causes the release of histamine from basophils and activates eosinophils, HIV-2, May activate several chemokine receptors including CCR1, May also be an agonist of the G protein-coupled receptor GPR75, One of the major HIV-suppressive factors produced by CD8+ T-cells, PubMed:13864, PubMed:15923218), PubMed:8525373, PubMed:9516414, Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection, The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:1679162, Together with GPR75, and simian immunodeficiency virus (SIV), may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, memory T-helper cells and eosinophils, stimulating inositol trisphosphate production and calcium mobilization through its activation, Chemoattractant for blood monocytes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
480, 565nm/578nm |
| Synonyms: |
RANTES SISd TCP228 MGC17164 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCL5/RANTES PE Conjugated |
| Short name: |
PE Conjugated, CCL5/RANTES Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
PE |
| Alternative name: |
peroxidase coupled, CCL5/RANTES (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10632 |
| Gene: |
CCL5 |
More about : CCL5 |
| Long gene name: |
C-C motif chemokine ligand 5 |
| Synonyms gene: |
D17S136E SCYA5 |
| Synonyms gene name: |
small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5 |
| Synonyms name: |
T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed |
| Locus: |
17q12 |
| Discovery year: |
1990-07-05 |
| GenBank acession: |
AF043341 |
| Entrez gene record: |
6352 |
| Pubmed identfication: |
1691736 |
| RefSeq identity: |
NM_002985 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000188396 |