| Long name: |
Cy5, 5 Conjugated, FZR1/CDC20C Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FZR1/CDC20C |
| Specificity: |
This is a highly specific antibody against FZR1/CDC20C |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
150-200/496 |
| Subcellular location: |
Intracellular, Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human FZR1/CDC20C |
| Gene ID number: |
51343 |
| Swiss Prot: |
Q9UM11 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Associates with the APC/C in late mitosis, At the G1/S transition FZR1 is phosphorylated, Following DNA damage, The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely, and activates the APC/C during anaphase and telophase, in replacement of CDC20, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, leading to its dissociation from the APC/C, preventing entry into mitosis, which confers substrate specificity upon the complex, Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
HCDH1 CDH1 HCDH FZR FZR2 KIAA1242 CDC20C |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
FZR1/CDC20C Conjugated |
| Short name: |
Conjugated, FZR1/CDC20C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, FZR1/CDC20C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24824 |
| Gene: |
FZR1 |
More about : FZR1 |
| Long gene name: |
fizzy and cell division cycle 20 related 1 |
| Synonyms gene name: |
fizzy/cell division cycle 20 related 1 (Drosophila) fizzy/cell division cycle 20 related 1 |
| Synonyms name: |
CDC20 homolog 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2004-03-31 |
| GenBank acession: |
AF083810 |
| Entrez gene record: |
51343 |
| Pubmed identfication: |
9734353 11003657 |
| RefSeq identity: |
NM_016263 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180747 |