| Long name: |
ALEXA FLUOR 647 Conjugated, FZR1/CDC20C Polyclonal Antibody |
| Also known as: |
Anti-FZR1/CDC20C PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FZR1/CDC20C |
| Specificity: |
This is a highly specific antibody against FZR1/CDC20C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
150-200/496 |
| Subcellular location: |
Intracellular, Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FZR1/CDC20C |
| Gene ID Number: |
51343 |
| Swiss Prot: |
Q9UM11 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Associates with the APC/C in late mitosis, At the G1/S transition FZR1 is phosphorylated, Following DNA damage, The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely, and activates the APC/C during anaphase and telophase, in replacement of CDC20, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, leading to its dissociation from the APC/C, preventing entry into mitosis, which confers substrate specificity upon the complex, Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
HCDH1 CDH1 HCDH FZR FZR2 KIAA1242 CDC20C |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the FZR1/CDC20C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
FZR1/CDC20C |
| Short name: |
FZR1/CDC20C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, FZR1/CDC20C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24824 |
| Gene: |
FZR1 |
More about : FZR1 |
| Long gene name: |
fizzy and cell division cycle 20 related 1 |
| Synonyms gene name: |
fizzy/cell division cycle 20 related 1 (Drosophila) fizzy/cell division cycle 20 related 1 |
| Synonyms name: |
CDC20 homolog 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2004-03-31 |
| GenBank acession: |
AF083810 |
| Entrez gene record: |
51343 |
| Pubmed identfication: |
9734353 11003657 |
| RefSeq identity: |
NM_016263 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180747 |