| Long name: |
ALEXA FLUOR 488 Conjugated, FTS/AKTIP Polyclonal Antibody |
| Also known as: |
Anti-FTS/AKTIP PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FTS/AKTIP |
| Specificity: |
This is a highly specific antibody against FTS/AKTIP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FTS/AKTIP |
| Gene ID Number: |
64400 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A member of the ubiquitin-conjugating enzyme family, AKT1 is a protein that plays a critical role in a number of cellular responses, FTS binds directly to AKT1 to regulate apoptosis in a cell population, The interaction of FTS and AKT1 enhances the phosphorylation and activation of AKT1, also known as AKT-interacting protein (AKTIP) and Ft1, and antiapoptotic signaling, is a 292 amino acid protein that localizes to the cytoplasm and the cell membrane, protein synthesis, results in the increased production of the proapoptotic hormone Fas ligand and thus an increase in apoptosis, such as cell growth, through an AKT1/GSK-3â, which, &circ, «, /NFATc1 signaling cascade, Fused toes protein homolog (FTS) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
FLJ13258 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FTS/AKTIP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
FTS/AKTIP |
| Short name: |
FTS/AKTIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, FTS/AKT interacting protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AKTIP and IDBG-31049 and ENSG00000166971 and 64400, AKTIP and IDBG-631788 and ENSBTAG00000016250 and 540462, Aktip and IDBG-179747 and ENSMUSG00000031667 and 14339, Plasma membranes, acid-amino acid ligase activity, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007032 and endosome organization and biological process this GO :0007040 and lysosome organization and biological process this GO :0008152 and metabolic process and biological process this GO :0008333 and endosome to lysosome transport and biological process this GO :0015031 and protein transport and biological process this GO :0016881 and acid-amino acid ligase activity and molecular function this GO :0030897 and HOPS complex and cellular component this GO :0032092 and positive regulation of protein binding and biological process this GO :0045022 and early endosome to late endosome transport and biological process this GO :0070695 and FHF complex and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0016881 : acid-amino acid ligase activity, this GO :0016881 : acid-amino acid ligase activity, AKT interacting protein |
| Identity: |
16710 |
| Gene: |
AKTIP |
More about : AKTIP |
| Long gene name: |
AKT interacting protein |
| Synonyms gene: |
FTS |
| Synonyms gene name: |
fused toes (mouse) homolog fused toes homolog (mouse) |
| Locus: |
16q12, 2 |
| Discovery year: |
2001-10-02 |
| GenBank acession: |
AK023320 |
| Entrez gene record: |
64400 |
| Pubmed identfication: |
7818539 8626685 |
| RefSeq identity: |
NM_022476 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000133199 |