| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FTS/AKTIP |
| Specificity: |
This antibody reacts specifically with FTS/AKTIP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FTS/AKTIP |
| Gene ID: |
64400 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A member of the ubiquitin-conjugating enzyme family, AKT1 is a protein that plays a critical role in a number of cellular responses, FTS binds directly to AKT1 to regulate apoptosis in a cell population, The interaction of FTS and AKT1 enhances the phosphorylation and activation of AKT1, also known as AKT-interacting protein (AKTIP) and Ft1, and antiapoptotic signaling, is a 292 amino acid protein that localizes to the cytoplasm and the cell membrane, protein synthesis, results in the increased production of the proapoptotic hormone Fas ligand and thus an increase in apoptosis, such as cell growth, through an AKT1/GSK-3â, which, &circ, «, /NFATc1 signaling cascade, Fused toes protein homolog (FTS) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ13258 |
| Also known as: |
FTS/AKTIP Polyclonal Antibody |
| Other name: |
Anti-FTS/AKTIP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FTS/AKTIP |
| Short name: |
Anti-FTS/AKTIP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FTS/AKT interacting protein (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AKTIP and IDBG-31049 and ENSG00000166971 and 64400, AKTIP and IDBG-631788 and ENSBTAG00000016250 and 540462, Aktip and IDBG-179747 and ENSMUSG00000031667 and 14339, Plasma membranes, acid-amino acid ligase activity, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007032 and endosome organization and biological process this GO :0007040 and lysosome organization and biological process this GO :0008152 and metabolic process and biological process this GO :0008333 and endosome to lysosome transport and biological process this GO :0015031 and protein transport and biological process this GO :0016881 and acid-amino acid ligase activity and molecular function this GO :0030897 and HOPS complex and cellular component this GO :0032092 and positive regulation of protein binding and biological process this GO :0045022 and early endosome to late endosome transport and biological process this GO :0070695 and FHF complex and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0016881 : acid-amino acid ligase activity, this GO :0016881 : acid-amino acid ligase activity, AKT interacting protein |
| Identity: |
16710 |
| Gene: |
AKTIP |
More about : AKTIP |
| Long gene name: |
AKT interacting protein |
| Synonyms gene: |
FTS |
| Synonyms gene name: |
fused toes (mouse) homolog fused toes homolog (mouse) |
| Locus: |
16q12, 2 |
| Discovery year: |
2001-10-02 |
| GenBank acession: |
AK023320 |
| Entrez gene record: |
64400 |
| Pubmed identfication: |
7818539 8626685 |
| RefSeq identity: |
NM_022476 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000133199 |