| Long name: |
Biotin Conjugated, Ficolin 2/Ficolin B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Ficolin 2/Ficolin B |
| Specificity: |
This is a highly specific antibody against Ficolin 2/Ficolin B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Ficolin 2/Ficolin B |
| Gene ID number: |
2220 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
EBP-37 or hucolin, Ficolin B binds to DNA ligands expressed by late apoptotic and necrotic cells to increase attachment and engulfment, Ficolin B is a 313 amino acid member of the ficolin lectin family, In patients with Behé, It is a secreted innate immunity pattern recognition molecule expressed in liver and plasma that forms a disulfide-linked homopolymer, This extensive N-terminal disulfide bridge formation can lead to a functional dodecamer polypeptide, Variation in ficolin B concentrations amongst individuals is associated with polymorphisms in the promoter and structural portion of the FCN2 gene, collagen/fibrinogen domain-containing protein 2, ficolin-2, serum lectin p35, there exists a significant difference in allele frequency for FCN2 gene single nucleotide polymorphisms (SNPs) within the -557 and -64 promoter sites within HLA-B51 positive and HLA-B51 negative subgroups, Ficolin B is the designation in mouse and rat of a protein also known as L-ficolin, t's disease (BD), ´ |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Collagen/fibrinogen domain containing protein 2, Collagen/fibrinogen domain-containing protein 2, EBP 37, EBP-37, EBP37, FCN 2, FCN2_HUMAN, FCNL, Fcn2, Ficolin B, Ficolin beta, Ficolin collagen/fibrinogen domain containing lectin 2 hucolin, Ficolin-2, Ficolin-B, Ficolin-beta, Ficolin2, Hucolin, L ficolin, L-ficolin, OTTHUMP00000022518, P35, RP11 263F14, Serum lectin p35, 2, 37 kDa elastin-binding protein |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Ficolin 2/Ficolin B Conjugated |
| Short name: |
Conjugated, Ficolin 2/Ficolin B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Ficolin 2/Ficolin B (Antibody to) |
| Alternative technique: |
antibodies |