| Long name: |
Ficolin 2/Ficolin B Primary Polyclonal Antibody |
| Also known as: |
Ficolin 2/Ficolin B PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Ficolin 2/Ficolin B |
| Specificity: |
This is a highly specific antibody against Ficolin 2/Ficolin B |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ficolin 2/Ficolin B |
| Gene ID number: |
2220 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
EBP-37 or hucolin, Ficolin B binds to DNA ligands expressed by late apoptotic and necrotic cells to increase attachment and engulfment, Ficolin B is a 313 amino acid member of the ficolin lectin family, In patients with Behé, It is a secreted innate immunity pattern recognition molecule expressed in liver and plasma that forms a disulfide-linked homopolymer, This extensive N-terminal disulfide bridge formation can lead to a functional dodecamer polypeptide, Variation in ficolin B concentrations amongst individuals is associated with polymorphisms in the promoter and structural portion of the FCN2 gene, collagen/fibrinogen domain-containing protein 2, ficolin-2, serum lectin p35, there exists a significant difference in allele frequency for FCN2 gene single nucleotide polymorphisms (SNPs) within the -557 and -64 promoter sites within HLA-B51 positive and HLA-B51 negative subgroups, Ficolin B is the designation in mouse and rat of a protein also known as L-ficolin, t's disease (BD), ´ |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Collagen/fibrinogen domain containing protein 2, Collagen/fibrinogen domain-containing protein 2, EBP 37, EBP-37, EBP37, FCN 2, FCN2_HUMAN, FCNL, Fcn2, Ficolin B, Ficolin beta, Ficolin collagen/fibrinogen domain containing lectin 2 hucolin, Ficolin-2, Ficolin-B, Ficolin-beta, Ficolin2, Hucolin, L ficolin, L-ficolin, OTTHUMP00000022518, P35, RP11 263F14, Serum lectin p35, 2, 37 kDa elastin-binding protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Ficolin 2/Ficolin B |
| Short name: |
Ficolin 2/Ficolin B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Ficolin 2/Ficolin B (Antibody to) |
| Alternative technique: |
antibodies |