| Long name: |
ALEXA FLUOR 647 Conjugated, Dynamin 1 Polyclonal Antibody |
| Also known as: |
Anti-Dynamin 1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Dynamin 1 |
| Specificity: |
This is a highly specific antibody against Dynamin 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dynamin 1 |
| Gene ID Number: |
1759 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Dephosphorylation is required for synaptic vesicle retrieval, Dynamin I is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C (PKC) (2â, Mouse, The phosphorylation site in PKC-phosphorylated Dynamin I is a single site at Serine 795, by Cdk5, including Ser 778, rat and human Dynamin I are phosphorylated on serine residues, regulating PACSIN1 recruitment and enabling synaptic vesicle endocytosis, suggesting that phosphorylation affects the subcellular localization of Dynamin I (5), the regulatory subunit of phosphatidylinositol 3-kinase (2â, which is located near a binding site for the SH3 domain of p85, &euro, &euro, &ldquo, &ldquo, 5), 5), Dynamin I is a GTPase enzyme required for the retrieval of synaptic vesicles after exocytosis and functions in endocytosis by stimulating assembly of invaginating synaptic vesicles (1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Dynamin 1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Dynamin 1 |
| Short name: |
Dynamin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Dynamin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2972 |
| Gene: |
DNM1 |
More about : DNM1 |
| Long gene name: |
dynamin 1 |
| Synonyms gene: |
DNM |
| Locus: |
9q34, 11 |
| Discovery year: |
1992-07-09 |
| GenBank acession: |
L07807 |
| Entrez gene record: |
1759 |
| Pubmed identfication: |
2144893 9143509 |
| RefSeq identity: |
NM_004408 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020733 |