| Long name: |
ALEXA FLUOR 350 Conjugated, Dynamin 1 Polyclonal Antibody |
| Also known as: |
Anti-Dynamin 1 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Dynamin 1 |
| Specificity: |
This is a highly specific antibody against Dynamin 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dynamin 1 |
| Gene ID Number: |
1759 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Dephosphorylation is required for synaptic vesicle retrieval, Dynamin I is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C (PKC) (2â, Mouse, The phosphorylation site in PKC-phosphorylated Dynamin I is a single site at Serine 795, by Cdk5, including Ser 778, rat and human Dynamin I are phosphorylated on serine residues, regulating PACSIN1 recruitment and enabling synaptic vesicle endocytosis, suggesting that phosphorylation affects the subcellular localization of Dynamin I (5), the regulatory subunit of phosphatidylinositol 3-kinase (2â, which is located near a binding site for the SH3 domain of p85, &euro, &euro, &ldquo, &ldquo, 5), 5), Dynamin I is a GTPase enzyme required for the retrieval of synaptic vesicles after exocytosis and functions in endocytosis by stimulating assembly of invaginating synaptic vesicles (1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Dynamin 1 |
| Short name: |
Dynamin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Dynamin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2972 |
| Gene: |
DNM1 |
More about : DNM1 |
| Long gene name: |
dynamin 1 |
| Synonyms gene: |
DNM |
| Locus: |
9q34, 11 |
| Discovery year: |
1992-07-09 |
| GenBank acession: |
L07807 |
| Entrez gene record: |
1759 |
| Pubmed identfication: |
2144893 9143509 |
| RefSeq identity: |
NM_004408 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020733 |