| Long name: |
DRIL1/ARID3A Primary Polyclonal Antibody |
| Also known as: |
DRIL1/ARID3A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DRIL1/ARID3A |
| Specificity: |
This is a highly specific antibody against DRIL1/ARID3A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DRIL1/ARID3A |
| Gene ID number: |
1820 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ARID3A is developmentally regulated and is expressed in a restricted set of cells, ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes, E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region, E2FBP1 appears to lack DNA binding and transactivation domains, The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1, are the mammalian homologs of the Drosophila Dri (dead ringer) protein, including differentiating cells of the gut and salivary glands, including gastrointestinal cancer, it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, ARID3A |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ARID domain-containing protein 3A, ARID3A, AT rich interactive domain-containing protein 3A, AT-rich interactive domain-containing protein 3A, B cell regulator of IgH transcription, B-cell regulator of IgH transcription, Bright, DRIL1, DRIL3, Dead ringer-like protein 1, E2F binding protein 1, E2F-binding protein 1, E2FBP1, dead ringer like 1, ARI3A_HUMAN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DRIL1/ARID3A |
| Short name: |
DRIL1/ARID3A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DRIL1/ARID3A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3031 |
| Gene: |
ARID3A |
More about : ARID3A |
| Long gene name: |
AT-rich interaction domain 3A |
| Synonyms gene: |
DRIL1 |
| Synonyms gene name: |
dead ringer-like 1 (Drosophila) AT rich interactive domain 3A (BRIGHT- like) AT rich interactive domain 3A (BRIGHT-like) |
| Synonyms: |
BRIGHT |
| Locus: |
19p13, 3 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
U88047 |
| Entrez gene record: |
1820 |
| Pubmed identfication: |
9722953 |
| RefSeq identity: |
NM_005224 |
| Classification: |
AT-rich interaction domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182018 |