| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DRIL1/ARID3A |
| Specificity: |
This antibody reacts specifically with DRIL1/ARID3A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DRIL1/ARID3A |
| Gene ID: |
1820 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ARID3A is developmentally regulated and is expressed in a restricted set of cells, ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes, E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region, E2FBP1 appears to lack DNA binding and transactivation domains, The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1, are the mammalian homologs of the Drosophila Dri (dead ringer) protein, including differentiating cells of the gut and salivary glands, including gastrointestinal cancer, it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, ARID3A |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BRIGHT |
| Also known as: |
DRIL1/ARID3A Polyclonal Antibody |
| Other name: |
Anti-DRIL1/ARID3A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DRIL1/ARID3A |
| Short name: |
Anti-DRIL1/ARID3A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DRIL1/ARID3A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3031 |
| Gene: |
ARID3A |
More about : ARID3A |
| Long gene name: |
AT-rich interaction domain 3A |
| Synonyms gene: |
DRIL1 |
| Synonyms gene name: |
dead ringer-like 1 (Drosophila) AT rich interactive domain 3A (BRIGHT- like) AT rich interactive domain 3A (BRIGHT-like) |
| Locus: |
19p13, 3 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
U88047 |
| Entrez gene record: |
1820 |
| Pubmed identfication: |
9722953 |
| RefSeq identity: |
NM_005224 |
| Classification: |
AT-rich interaction domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182018 |