| Long name: |
Cy5, 5 Conjugated, Dnmt2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Dnmt2 |
| Specificity: |
This is a highly specific antibody against Dnmt2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Dnmt2 |
| Gene ID number: |
1787 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3, DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, Dnmt1 is the most abundant, Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, Dnmt3a and Dnmt3b are encoded by two distinct genes, The Dnmt enzymes are encoded by independent genes, and is likely involved in methylating newly integrated retroviral DNA, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development, and this methylation results in transcriptional repression of the target gene, but both are abundantly expressed in embryonic stem cells, is expressed at substantially lower levels in adult tissues, where they also methylate CpG motifs on DNA, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
DNA 5 cytosine methyltransferase, DNA MTase homolog HsaIIP, DNA cytosine 5 methyltransferase 2, DNA cytosine 5 methyltransferase like protein 2, DNA cytosine-5-methyltransferase-like protein 2, DNA methyltransferase 2, DNA methyltransferase homolog HsaIIP, DmMT 2, DmMT2, Dnmt 2, Dnmt2, M, MHsaIIP, OTTHUMP00000045198, PuMet, RNMT 1, RNMT1, TRDMT 1, TRDMT1, TRDMT_HUMAN, nmt 2, nmt2, tRNA aspartic acid methyltransferase 1, tRNA aspartic acid methyltransferase 1 variant 1, tRNA aspartic acid methyltransferase 1 variant 2, tRNA aspartic acid methyltransferase 1 variant 3, tRNA aspartic acid methyltransferase 1 variant 4, tRNA aspartic acid methyltransferase 1 variant 5, tRNA aspartic acid methyltransferase 1 variant 8, tRNA cytosine 5 methyltransferase, tRNA cytosine38-C5-methyltransferase, HsaIIP, dDNMT |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
Dnmt2 Conjugated |
| Short name: |
Conjugated, Dnmt2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, Dnmt2 (Antibody to) |
| Alternative technique: |
antibodies |