| Long name: |
ALEXA FLUOR 647 Conjugated, Dnmt2 Polyclonal Antibody |
| Also known as: |
Anti-Dnmt2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Dnmt2 |
| Specificity: |
This is a highly specific antibody against Dnmt2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt2 |
| Gene ID Number: |
1787 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3, DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, Dnmt1 is the most abundant, Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, Dnmt3a and Dnmt3b are encoded by two distinct genes, The Dnmt enzymes are encoded by independent genes, and is likely involved in methylating newly integrated retroviral DNA, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development, and this methylation results in transcriptional repression of the target gene, but both are abundantly expressed in embryonic stem cells, is expressed at substantially lower levels in adult tissues, where they also methylate CpG motifs on DNA, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
RNMT1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Dnmt2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Dnmt2 |
| Short name: |
Dnmt2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Dnmt2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2977 |
| Gene: |
TRDMT1 |
More about : TRDMT1 |
| Long gene name: |
tRNA aspartic acid methyltransferase 1 |
| Synonyms gene: |
DNMT2 |
| Synonyms gene name: |
DNA (cytosine-5-)-methyltransferase 2 |
| Synonyms name: |
tRNA (cytosine(38)-C(5))-methyltransferase |
| Locus: |
10p13 |
| Discovery year: |
1998-05-07 |
| GenBank acession: |
AJ223333 |
| Entrez gene record: |
1787 |
| Pubmed identfication: |
9425235 9763678 16424344 |
| RefSeq identity: |
NM_004412 |
| Havana BLAST/BLAT: |
OTTHUMG00000017745 |