| Long name: |
Cy5 Conjugated, DNA Polymerase iota Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DNA Polymerase iota |
| Specificity: |
This is a highly specific antibody against DNA Polymerase iota |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DNA Polymerase iota |
| Gene ID number: |
11201 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At thymine templates, DNA Pol i acts sequentially with DNA Pol Î, DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, DNA polymerases can often bypass DNA lesions that block DNA replication, One such DNA polymerase is the distributive enzyme DNA Pol i, POLI is located on human chromosome 18q21, Therefore, a region often implicated in the etiology of many human cancers, adenosine, recombination and mutagenesis, repair, replication involving DNA Pol i is likely to be highly mutagenic, thereby allowing the replication of damaged DNA, to complete the DNA lesion bypass, which is encoded by the POLI gene, which is essential for damage-induced mutagenesis, ©, 2, DNA polymerase activity is essential for replication |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
Eta 2, Eta2, POLI, POLI_HUMAN, Polymerase DNA directed iota, RAD 30B, RAD30 homolog B, RAD30B, RAD3OB, DNA polymerase iota |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DNA Polymerase iota Conjugated |
| Short name: |
Conjugated, DNA Polymerase iota Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, Desoxyribonucleic acid polymerizing enzyme iota (Antibody to) |
| Alternative technique: |
antibodies |