CSK (Ser364) Antibody

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Catalog number: bs-12942R
Price: 368 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: CSK (Ser364) Antibody
Quantity: 0.1ml
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More details :

Long name: CSK (Ser364) Primary Polyclonal Antibody
Also known as: CSK (Ser364) PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: CSK Ser364
Specificity: This is a highly specific antibody against CSK Ser364
Modification(s): Phosphorylation
Modification site(s): Ser364
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human CSK around the phosphorylation site of Ser364
Gene ID number: 1445
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences, Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites, In the case of Src p60, Y527 is this tyrosine, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart, however, All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: C SRC, C SRC kinase, C src Tyrosine Kinase, C-SRC kinase, CSK, CSK_HUMAN, CYTOPLASMIC TYROSINE KINASE, Csk A, EC 2, MGC112926, MGC117393, MGC154049, P60 Src, Protein tyrosine kinase CYL, Protein-tyrosine kinase CYL, Proto oncogene tyrosine protein kinase, Tyrosine protein kinase CSK, Tyrosine-protein kinase CSK, c-src tyrosine kinase, p-CSKphospho S364, zgc:154049, 2, 7, 10, CSKphospho S364
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: CSK (Ser364)
Short name: CSK (Ser364) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: CSK (Ser364) (Antibody to)
Alternative technique: antibodies
Identity: 2444
Gene: CSK | More about : CSK
Long gene name: CSK, non-receptor tyrosine kinase
Synonyms gene name: c-src tyrosine kinase
Locus: 15q24, 1
Discovery year: 1992-03-20
Entrez gene record: 1445
Pubmed identfication: 1377109
RefSeq identity: NM_004383
Classification: SH2 domain containing
Havana BLAST/BLAT: OTTHUMG00000142814

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