Anti-CSK (Ser364) (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be5cefaf53c Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Anti-CSK (Ser364) (Polyclonal), ALEXA Fluor 594
Quantity:	0.1ml
Related search:	csk polyclonal antibody tyrosine src terminal nbsp sequences

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	CSK Ser364
Specificity:	This antibody reacts specifically with CSK (Ser364)
Modification:	Phosphorylation
Modification site:	Ser364
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic phosphopeptide derived from human CSK around the phosphorylation site of Ser364
Gene ID:	1445
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences, Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites, In the case of Src p60, Y527 is this tyrosine, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart, however, All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Also known as:	CSK (Ser364) Polyclonal Antibody
Other name:	Anti-CSK (Ser364) Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	CSK (Ser364)
Short name:	Anti-CSK (Ser364) (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-CSK (Ser364) (polyclonal)
Alternative technique:	polyclonals
Identity:	2444
Gene:	CSK | More about : CSK
Long gene name:	CSK, non-receptor tyrosine kinase
Synonyms gene name:	c-src tyrosine kinase
Locus:	15q24, 1
Discovery year:	1992-03-20
Entrez gene record:	1445
Pubmed identfication:	1377109
RefSeq identity:	NM_004383
Classification:	SH2 domain containing
Havana BLAST/BLAT:	OTTHUMG00000142814

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• #terminal
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• #sequences