| Long name: |
ALEXA FLUOR 594 Conjugated, CYP1B1 Polyclonal Antibody |
| Also known as: |
Anti-CYP1B1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CYP1B1 |
| Specificity: |
This is a highly specific antibody against CYP1B1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
450-485/543 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP1B1 |
| Gene ID Number: |
1545 |
| Swiss Prot: |
Q16678 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression, In liver microsomes, It oxidizes a variety of structurally unrelated compounds, Plays an important role in the regulation of perivascular cell proliferation, Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, Promotes angiogenesis by removing cellular oxygenation products, These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis, and a variety of procarcinogenic compounds to their activated forms, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, cell adhesion and capillary morphogenesis, during angiogenesis, fatty acids, including polycyclic aromatic hydrocarbons, including steroids, migration, release of antiangiogenic factor THBS2, retinoid and xenobiotics, then allowing endothelial cells migration, thereby decreasing oxidative stress, this enzyme is involved in an NADPH-dependent electron transport pathway, Cytochromes P450 are a group of heme-thiolate monooxygenases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CP1B |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
CYP1B1 |
| Short name: |
CYP1B1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, CYP1B1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2597 |
| Gene: |
CYP1B1 |
More about : CYP1B1 |
| Long gene name: |
cytochrome P450 family 1 subfamily B member 1 |
| Synonyms gene: |
GLC3A |
| Synonyms gene name: |
cytochrome P450, family 1, polypeptide 1 , polypeptide 1 (glaucoma 3, primary infantile) cytochrome P450, subfamily B, subfamily I (dioxin-inducible) |
| Locus: |
2p22, 2 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
U56438 |
| Entrez gene record: |
1545 |
| Pubmed identfication: |
8175734 15128046 |
| RefSeq identity: |
NM_000104 |
| Classification: |
Cytochrome P450 family 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000100970 |
| Locus Specific Databases: |
Human Cytochrome P450 (CYP)Allele Nomenclature Committee |