| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CYP1B1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the CYP1B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CYP1B1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q16678 |
| Purity: |
Purified |
| Description: |
Mutations in CYP1B1 gene have been associated with primary congenital glaucoma, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The enzyme localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol, possibly a steroid, steroids and other lipids, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, CYP1B1 is a member of the cytochrome P450 superfamily of enzymes |
| Immunogen: |
A portion of amino acids 143-176 from the human protein was used as the immunogen for this CYP1B1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CYP1B1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CYP1B1 |
| Short name: |
CYP1B1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CYP1B1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2597 |
| Gene: |
CYP1B1 |
More about : CYP1B1 |
| Long gene name: |
cytochrome P450 family 1 subfamily B member 1 |
| Synonyms gene: |
GLC3A |
| Synonyms gene name: |
cytochrome P450, family 1, polypeptide 1 , polypeptide 1 (glaucoma 3, primary infantile) cytochrome P450, subfamily B, subfamily I (dioxin-inducible) |
| Synonyms: |
CP1B |
| Locus: |
2p22, 2 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
U56438 |
| Entrez gene record: |
1545 |
| Pubmed identfication: |
8175734 15128046 |
| RefSeq identity: |
NM_000104 |
| Classification: |
Cytochrome P450 family 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000100970 |
| Locus Specific Databases: |
Human Cytochrome P450 (CYP)Allele Nomenclature Committee |