| Long name: |
CYP2A/Cytochrome P450 2A6 Antibody |
| Also known as: |
CYP2A/Cytochrome P450 2A6 Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CYP2A/Cytochrome P450 2A6 |
| Specificity: |
This is a highly specific antibody against CYP2A/Cytochrome P450 2A6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP2A/Cytochrome P450 2A6 |
| Gene ID number: |
1548 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle (3, NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome b5 (5, NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies (2), ferredoxin nucleotide reductase (FNR) and flavodoxin (7), respectively (8), to the FNR and flavodoxin domains, 4), 6), P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CP2A6_HUMAN, CPA6, CYP2A, CYP2A3, CYP2A6, CYPIIA6, Coumarin 7-hydroxylase, Cytochrome P450, Cytochrome P450 2A6, Cytochrome P450 IIA3, Cytochrome P450 subfamily IIA phenobarbital inducible polypeptide 6, Cytochrome P450I, Flavoprotein linked monooxygenase, P450C2A, P450PB, Xenobiotic monooxygenase, family 2 subfamily A polypeptide 6, Coumarin 7 hydroxylase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CYP2A/Cytochrome P450 2A6 |
| Short name: |
CYP2A/Cytochrome P450 2A6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CYP2A/Cytochrome P450 2A6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2611 |
| Gene: |
CYP2A7 |
More about : CYP2A7 |
| Long gene name: |
cytochrome P450 family 2 subfamily A member 7 |
| Synonyms gene name: |
cytochrome P450, family 2, polypeptide 7 , polypeptide 7 cytochrome P450, subfamily A, subfamily IIA (phenobarbital-inducible) |
| Synonyms: |
CYP2A |
| Locus: |
19q13, 2 |
| Discovery year: |
1995-12-13 |
| GenBank acession: |
NM_000764 |
| Entrez gene record: |
1549 |
| Pubmed identfication: |
7668294 15128046 |
| RefSeq identity: |
NM_030589 |
| Classification: |
Cytochrome P450 family 2 |
| Havana BLAST/BLAT: |
OTTHUMG00000182715 |