| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CYP2A/Cytochrome P450 2A6 |
| Specificity: |
This antibody reacts specifically with CYP2A/Cytochrome P450 2A6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CYP2A/Cytochrome P450 2A6 |
| Gene ID: |
1548 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle (3, NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome b5 (5, NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies (2), ferredoxin nucleotide reductase (FNR) and flavodoxin (7), respectively (8), to the FNR and flavodoxin domains, 4), 6), P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds (1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CYP2A |
| Also known as: |
CYP2A/Cytochrome P450 2A6 Antibody |
| Other name: |
Anti-CYP2A/Cytochrome P450 2A6 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CYP2A/Cytochrome P450 2A6 |
| Short name: |
Fluor 594, Anti-CYP2A/Cytochrome P450 2A6 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CYP2A/Cytochrome P450 2A6 |
| Identity: |
2611 |
| Gene: |
CYP2A7 |
More about : CYP2A7 |
| Long gene name: |
cytochrome P450 family 2 subfamily A member 7 |
| Synonyms gene name: |
cytochrome P450, family 2, polypeptide 7 , polypeptide 7 cytochrome P450, subfamily A, subfamily IIA (phenobarbital-inducible) |
| Locus: |
19q13, 2 |
| Discovery year: |
1995-12-13 |
| GenBank acession: |
NM_000764 |
| Entrez gene record: |
1549 |
| Pubmed identfication: |
7668294 15128046 |
| RefSeq identity: |
NM_030589 |
| Classification: |
Cytochrome P450 family 2 |
| Havana BLAST/BLAT: |
OTTHUMG00000182715 |