| Long name: |
Cy3 Conjugated, c-Kit (Tyr730) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
c-Kit Tyr730 |
| Specificity: |
This is a highly specific antibody against c-Kit Tyr730 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr730 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr730 |
| Gene ID number: |
3815 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Ewing sarcoma and lung cancer, Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase, acute myeloid leukemia, and activation, apoptosis, c-Kit acts to regulate a variety of biological responses including cell proliferation, chemotaxis and adhesion, gastrointestinal stromal tumor, c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
C Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, Stem cell factor receptor, Tyrosine-protein kinase Kit, c-Kit, c-Kit phospho Tyr730, p-c-Kit Tyr 730, p145 c-kit, soluble KIT variant 1, tyrosine protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, c-Kit phospho Y730 |
| Properties: |
1 of the c-Kit (Tyr730) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
c-Kit (Tyr730) Conjugated |
| Short name: |
Conjugated, c-Kit (Tyr730) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, c-reagent (Tyr730) (Antibody to) |
| Alternative technique: |
antibodies |