| Catalog number: | bs-12914R |
|---|---|
| Price: | 2895 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | c-Kit (Tyr730) Antibody |
| Quantity: | 1000ug |
| Related search: |
| Long name: | c-Kit (Tyr730) Primary Polyclonal Antibody |
|---|---|
| Also known as: | c-Kit (Tyr730) PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | c-Kit Tyr730 |
| Specificity: | This is a highly specific antibody against c-Kit Tyr730 |
| Modification(s): | Phosphorylation |
| Modification site(s): | Tyr730 |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr730 |
| Gene ID number: | 3815 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Ewing sarcoma and lung cancer, Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase, acute myeloid leukemia, and activation, apoptosis, c-Kit acts to regulate a variety of biological responses including cell proliferation, chemotaxis and adhesion, gastrointestinal stromal tumor, c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | C Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, Stem cell factor receptor, Tyrosine-protein kinase Kit, c-Kit, c-Kit phospho Tyr730, p-c-Kit Tyr 730, p145 c-kit, soluble KIT variant 1, tyrosine protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, c-Kit phospho Y730 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | c-Kit (Tyr730) |
| Short name: | c-Kit (Tyr730) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | c-reagent (Tyr730) (Antibody to) |
| Alternative technique: | antibodies |
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