| Long name: |
GDF8/MSTN Primary Polyclonal Antibody |
| Also known as: |
GDF8/MSTN PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GDF8/MSTN |
| Specificity: |
This is a highly specific antibody against GDF8/MSTN |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
300-350/375 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDF8 |
| Gene ID number: |
2660 |
| Swiss Prot: |
O14793 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts specifically as a negative regulator of skeletal muscle growth, Belongs to the TGF-beta family, The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues, This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth, This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues, Weak expression in adipose tissue, [SUBUNIT] Homodimer, [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle, The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GDF-8, Growth/differentiation factor 8, MSLHP, MSTN, Myostatin, GDF8 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GDF8/MSTN |
| Short name: |
GDF8/MSTN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GDF8/myostatin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0048632 and negative regulation of skeletal muscle tissue growth and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process, Extracellular, GDF8 and MSLHP, MSTN and IDBG-639462 and ENSBTAG00000011808 and 281187, MSTN and IDBG-77438 and ENSG00000138379 and 2660, Mstn and IDBG-153903 and ENSMUSG00000026100 and 17700, identical protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007517 and muscle organ development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0009408 and response to heat and biological process this GO :0009629 and response to gravity and biological process this GO :0014732 and skeletal muscle atrophy and biological process this GO :0014741 and negative regulation of muscle hypertrophy and biological process this GO :0014850 and response to muscle activity and biological process this GO :0022602 and ovulation cycle process and biological process this GO :0033574 and response to testosterone and biological process this GO :0040007 and growth and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0043627 and response to estrogen and biological process this GO :0045471 and response to ethanol and biological process this GO :0045893 and positive regulation of transcription, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0008201 : heparin binding and also this GO :0042802 : identical protein binding, this GO :0005125 : cytokine activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0008201 : heparin binding, this GO :0042802 : identical protein binding, myostatin |
| Identity: |
4223 |
| Gene: |
MSTN |
More about : MSTN |
| Long gene name: |
myostatin |
| Synonyms gene: |
GDF8 |
| Synonyms gene name: |
growth differentiation factor 8 |
| Locus: |
2q32, 2 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
AF019627 |
| Entrez gene record: |
2660 |
| Pubmed identfication: |
9288100 10610713 17003236 |
| RefSeq identity: |
NM_005259 |
| Havana BLAST/BLAT: |
OTTHUMG00000132663 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy pages LRG_200 |