| Also known as: |
MSTN / GDF8 / Myostatin |
| Other names: |
GDF-8, Growth/differentiation factor 8, Myostatin, growth differentiation factor 8, growth/differentiation factor 8, myostatin, growth/differentiation factor 8 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MSTN |
| Other gene names: |
GDF-8, GDF8, GDF8, MSLHP, MSTN, MSTN |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
6H12 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human MSTN |
| Purification method: |
Ascites |
| Form/Appearance: |
0, Sourced in Ascites, 03% sodium azide, Ascites fluid |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 6H12] (IgG1) MSTN / GDF8 / Myostatin |
| Short name: |
Mouse Monoclonal [clone 6H12] (IgG1) MSTN / GDF8 / Myostatin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens myostatin / GDF8 / Myostatin (Antibody to), Mouse monoclonal [clonality 6H12] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0048632 and negative regulation of skeletal muscle tissue growth and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process, Extracellular, GDF8 and MSLHP, MSTN and IDBG-639462 and ENSBTAG00000011808 and 281187, MSTN and IDBG-77438 and ENSG00000138379 and 2660, Mstn and IDBG-153903 and ENSMUSG00000026100 and 17700, identical protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007517 and muscle organ development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0009408 and response to heat and biological process this GO :0009629 and response to gravity and biological process this GO :0014732 and skeletal muscle atrophy and biological process this GO :0014741 and negative regulation of muscle hypertrophy and biological process this GO :0014850 and response to muscle activity and biological process this GO :0022602 and ovulation cycle process and biological process this GO :0033574 and response to testosterone and biological process this GO :0040007 and growth and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0043627 and response to estrogen and biological process this GO :0045471 and response to ethanol and biological process this GO :0045893 and positive regulation of transcription, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0008201 : heparin binding and also this GO :0042802 : identical protein binding, this GO :0005125 : cytokine activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0008201 : heparin binding, this GO :0042802 : identical protein binding, myostatin |
| Identity: |
4223 |
| Gene: |
MSTN |
More about : MSTN |
| Long gene name: |
myostatin |
| Synonyms gene: |
GDF8 |
| Synonyms gene name: |
growth differentiation factor 8 |
| Locus: |
2q32, 2 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
AF019627 |
| Entrez gene record: |
2660 |
| Pubmed identfication: |
9288100 10610713 17003236 |
| RefSeq identity: |
NM_005259 |
| Havana BLAST/BLAT: |
OTTHUMG00000132663 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy pages LRG_200 |